Sorbitol is widely used as an excipient in pharmaceutical formulations. It is also used extensively in cosmetics and food products. Sorbitol is used as a diluent in tablet formulations prepared by either wet granulation or direct compression.It is particularly useful in chewable tablets owing to its pleasant, sweet taste and cooling sensation. In capsule formulations it is used as a plasticizer for gelatin. Sorbitol has been used as a plasticizer in film formulations. In liquid preparations sorbitol is used as a vehicle in sugar-free formulations and as a stabilizer for drug vitamin and antacid suspensions. Furthermore, sorbitol is used as an excipient in liquid parenteral biologic formulations to provide effective protein stabilization in the liquid state.