Glycerin

Glycerin is used in a wide variety of pharmaceutical formulations including oral, otic, ophthalmic, topical, and parenteral preparations. In topical pharmaceutical formulations and cosmetics, glycerin is used primarily for its humectant and emollient properties. Glycerin is used as a solvent or cosolvent in creams and emulsions. Glycerin is additionally used in aqueous and nonaqueous gels and also as an additive in patch applications. In parenteral formulations, glycerin is used mainly as a solvent and cosolvent. In oral solutions, glycerin is used as a solvent, sweetening agent, antimicrobial preservative, and viscosity-increasing agent. It is also used as a plasticizer and in film coatings. Glycerin is used as a plasticizer of gelatin in the production of soft-gelatin capsules and gelatin suppositories. Glycerin is employed as a therapeutic agent in a variety of clinical applications and is also used as a food additive. It is cosolvent, emollient, humectant, tonicity agent.

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